Free chemistry book: Organic synthesis wordbook 1,2,3
1.Oranic synthesis workbook I:
1. A. Gewert, 1. Gorlitzer, S. Gotze, 1. Looft
Foreword by Erick M. Carreira
2.Oranic synthesis workbook II:
We have not changed the proved original concept, and therefore we hope that those who already
know Organic Synthesis Workbook will feel at home.
This book contains 16 independent chapters, based on publications of well known scientists.
Each chapter is divided into five parts. First, the Introduction will give you a brief view of the
target molecule and its background. The Overview shows the complete synthetic problem on two
pages. In the Synthesis section the reaction sequence is divided ¡nto individual Problems.
Afterwards Hints are given to assist you in solving the problem. Each further hint will reveal more
and more of the solution; therefore it might be useful to cover the remaining page with a piece of
paper. The Solution will show if your answer is correct. In the Discussion section the problem is
explained in detail. However this book cannot serve as a substitute for an organic textbook. After
the last problem, the Conclusion briefly comments on the synthesis, highlighting the key steps.
The original references can be found in the Literature section for further reading.
Gewert, J.A./Gorlitzer, J./
Gotze, S./Looft, J./Menningen, P./
Nobel, T./Schirok, H./Wulff, C.
Organic Synthesis Workbook
2000. ISBN 3-527-30187-9
1996.308 pp. ISBN 3-527-29278-0
From Fundamentals to Research
1998.288 pp. ISBN 3-527-29755-3
Supramolecular ChemistryConcepts and Perspectives
1995. 2881JJp. ISBN 3-527-29311-6
Organic Synthesis Highlights 111
1998. ISBN 3-527-29500-3
Classics in Total Synthesis1996. ISBN 3-527-29231-4
3.Oranic synthesis workbook III:
Organic synthesis is at the heart of chemistry. Although today interdisciplinary areas between
chemistry and biology or between chemistry and material sciences are ofien believed to provide
the main driving forces for the advancement of chemistry, I am convinced that the development
of efficient and environmentally benign synthetic methods is still one of the most important goals
of current chemical research. Significantly, a majority of all chemists doing research in industry
or academia are faced in their daily lives with demands for the efficient synthesis of new
molecules. It is thus important to attract the interest of talented students for this area and to
provide high quality education. From the beginning, the Organic Synthesis Workbook has been
devoted to a significant extent to the training and education of students and younger researchers
in this direction. The main concept is to present challenging synthetic problems to the reader,
which are selected from state-of-the-art syntheses of natural products. The present 3rd volume
successfully follows this track.
The new Organic Synthesis Workbook – similar to its predecessors – has been carefully devised
and realized by a group of creative young students from the Institute of Organic and Biomolecular
Chemistry ofthe Georg-August-University ofGottingen, Germany.1t covers 14 wellselected
synthetic problems including modern catalytic coupling reactions and metathesis
chemistry, together with recent developments in stereoselective carbon-carbon and carbonoxygen
bond formation. More specifically, each problem is introduced to the reader in a general
marmer. Afier this introduction the key chemistry of the respective synthesis is explained. Then,
the various synthetic problems are presented in a clear and understandable manner. The major
difference to classical teaching books is the active interaction ofthe reader with the content.
One could ask, is the concept ofthis book still timely? In my opinion, definitely yes! Obviously,
information pours out from all kinds of scientific journals, PowerPoint presentations, and
especially the internet. However, to acquire long-Iasting knowledge of organic synthesis, and to
transfer this knowledge, it is essential not only to consume facts and data but to apply it to real
synthetic problems. Thus, in addition to students for Masters and PhD degrees, everyone
interested in synthetic chemistry is encouraged to train actively with books such as this.
Finally, 1 wish to congratulate the authors for their excellent achievement. It remains for me to
hope that readers will enjoy working with this volume and discover aspects that will stimulate
their own future research